Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721737 | 1.00 | HTR1B (0.50) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL19291642 | 1.00 | HTR1B (0.50) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL19291799 | 0.99 | HTR1B (0.51) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL25822091 | 0.96 | HTR1B (0.51) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL25822083 | 0.93 | HTR1B (0.54) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL25819231 | 0.86 | KDM4E (0.40) | HTR1BTLR4TLR2HTR1DCARM1 | |
| SCHEMBL25819794 | 0.84 | HTR2C (0.45) | TLR4TLR2CARM1PRMT6SIRT2 | |
| SCHEMBL4568767 | 0.84 | TLR4 (0.53) | TLR4TLR2KDM4EALDH1A1TDP1 | |
| SCHEMBL4568768 | 0.84 | TLR4 (0.53) | TLR4TLR2KDM4EALDH1A1TDP1 | |
| SCHEMBL4568904 | 0.84 | TLR4 (0.53) | TLR4TLR2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | HTR1B 960/4885TLR4 517/4885TLR2 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.