Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19293191 | 0.84 | PLA2G2A (0.31) | PLA2G2APLA2G4A | |
| SCHEMBL19293193 | 0.84 | PLA2G2A (0.31) | PLA2G2APLA2G4A | |
| SCHEMBL15866368 | 0.83 | PLA2G2A (0.33) | PLA2G2APLA2G4APLA2G10 | |
| SCHEMBL19293189 | 0.81 | RAB9A (0.31) | PLA2G2APLA2G4ARAB9A | |
| SCHEMBL27337735 | 0.77 | — | — | |
| SCHEMBL20654880 | 0.76 | PLA2G2A (0.30) | PLA2G2APLA2G4A | |
| SCHEMBL21431636 | 0.76 | PLA2G2A (0.30) | PLA2G2APLA2G4A | |
| SCHEMBL18965405 | 0.73 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL20821583 | 0.73 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10KDM4ENPC1 | |
| SCHEMBL20045015 | 0.73 | PLA2G2A (0.57) | PLA2G2APLA2G4APLA2G10KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3211682-A1 | AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FIELD | Idemitsu Kosan Co., Ltd (JP) | 2017-08-30 | — | — | EP | disclosed |