Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21031614 | 0.96 | OPRM1 (0.42) | OPRM1OPRL1PDE4DLRRK2PDK2 | |
| SCHEMBL17903090 | 0.93 | OPRM1 (0.41) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL12376870 | 0.93 | CA4 (0.39) | OPRM1OPRL1LRRK2PDK2KDM4E | |
| SCHEMBL16996132 | 0.92 | PDK2 (0.41) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL16996425 | 0.91 | PDK2 (0.40) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL21364231 | 0.91 | PDK2 (0.40) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL12545359 | 0.90 | PDE4D (0.39) | OPRM1OPRL1PDE4DLTA4H | |
| SCHEMBL22211030 | 0.90 | PDK2 (0.44) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL17805080 | 0.90 | PDK2 (0.45) | OPRM1OPRL1PDE4DPDK2KDM4E | |
| SCHEMBL22211047 | 0.89 | PDK2 (0.44) | OPRM1OPRL1PDE4DPDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956350-B2 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-7956350-B2 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-7482490-B2 | Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound | TOSOH CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TOSOH CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20070063191-A1 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| US-20070063191-A1 | Crosslinkable substituted fluorene compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
| WO-2005049548-A1 | CROSSLINKABLE SUBSTITUTED FLUORENE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TAAR1, SLC18A1, ADRB2 | OPRM1 91/4885OPRL1 38/4885PDE4D 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.