Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 5/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299415 | 0.89 | PTGDR2 (0.36) | PTGDR2CHRM1MEN1KMT2ARXFP1 | |
| SCHEMBL22544549 | 0.87 | EGFR (0.38) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL21207869 | 0.83 | SLC6A4 (0.40) | MEN1KMT2AHPGDMAP4K4SLC6A9 | |
| SCHEMBL22172107 | 0.82 | PGR (0.39) | CHRM1KMT2ALTB4RMAP4K4SLC6A9 | |
| SCHEMBL23018866 | 0.80 | GPR84 (0.37) | MEN1KMT2AMAPTHPGDCYP2C9 | |
| SCHEMBL19119685 | 0.78 | CYP2D6 (0.34) | CYP2C9 | |
| SCHEMBL23018775 | 0.77 | EGFR (0.40) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL19781091 | 0.77 | NPC1 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL23638849 | 0.77 | PPARG (0.33) | MEN1KMT2A | |
| SCHEMBL26048192 | 0.76 | PDE4B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2017144150-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | WO | disclosed |