Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544549 | 0.90 | EGFR (0.38) | EGFRMEN1APAF1NPC1LMNA | |
| SCHEMBL19299415 | 0.86 | PTGDR2 (0.36) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL24534331 | 0.85 | CYP11B1 (0.38) | MEN1MAPTKMT2AHSD17B1HSD17B2 | |
| SCHEMBL26048192 | 0.84 | PDE4B (0.33) | EGFRBACE1HPRT1 | |
| SCHEMBL23018866 | 0.82 | GPR84 (0.37) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL23018836 | 0.81 | KDM4E (0.30) | MAPT | |
| SCHEMBL19119685 | 0.81 | CYP2D6 (0.34) | EGFRRAB9APDCD1CD274ESR2 | |
| SCHEMBL21851587 | 0.79 | L3MBTL1 (0.38) | EGFRMEN1APAF1NPC1LMNA | |
| SCHEMBL18732907 | 0.79 | MEN1 (0.36) | MEN1KMT2AALOX5RXRARXRB | |
| SCHEMBL18371186 | 0.79 | RXRA (0.36) | MEN1LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |