Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299911 | 0.90 | KCNH2 (0.33) | RORCNPC1RAB9AKCNH2LMNA | |
| SCHEMBL19283559 | 0.90 | KCNH2 (0.37) | RORCNPC1RAB9AKCNH2LMNA | |
| SCHEMBL19299910 | 0.90 | KCNH2 (0.33) | RORCNPC1RAB9AKCNH2LMNA | |
| SCHEMBL18050222 | 0.89 | S1PR1 (0.34) | RORCKCNH2ALDH1A1HPGD | |
| SCHEMBL19299912 | 0.89 | KCNH2 (0.35) | RORCNPC1RAB9AKCNH2 | |
| SCHEMBL19299797 | 0.88 | MAPT (0.36) | RORCKCNH2LMNAKDM4EALDH1A1 | |
| SCHEMBL20547209 | 0.86 | KCNH2 (0.32) | RORCKCNH2 | |
| SCHEMBL21948872 | 0.84 | ADORA2A (0.33) | RORCNPC1RAB9AKCNH2LMNA | |
| SCHEMBL21875179 | 0.84 | KCNH2 (0.33) | RORCNPC1RAB9AKCNH2LMNA | |
| SCHEMBL29600219 | 0.84 | KCNH2 (0.33) | RORCNPC1RAB9AKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |