Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299911 | 0.93 | KCNH2 (0.33) | KCNH2RORCDDR1CNR2NPC1 | |
| SCHEMBL19299809 | 0.90 | RORC (0.34) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL19283559 | 0.87 | KCNH2 (0.37) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL18050222 | 0.86 | S1PR1 (0.34) | KCNH2RORCDDR1S1PR1 | |
| SCHEMBL19299912 | 0.86 | KCNH2 (0.35) | KCNH2RORCDDR1NPC1RAB9A | |
| SCHEMBL19299797 | 0.85 | MAPT (0.36) | KCNH2RORCDDR1LMNAHTT | |
| SCHEMBL21875179 | 0.83 | KCNH2 (0.33) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL21948872 | 0.83 | ADORA2A (0.33) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL29600219 | 0.83 | KCNH2 (0.33) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL20547209 | 0.83 | KCNH2 (0.32) | KCNH2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |