Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299811 | 0.93 | MAPT (0.35) | MAPTKMT2AMEN1GAATSHR | |
| SCHEMBL19299911 | 0.91 | KCNH2 (0.33) | DDR1KCNH2RORCLMNAHTT | |
| SCHEMBL19283559 | 0.91 | KCNH2 (0.37) | KCNH2RORCLMNAHTTSMN1; SMN2 | |
| SCHEMBL19299912 | 0.90 | KCNH2 (0.35) | DDR1KCNH2RORC | |
| SCHEMBL18050222 | 0.90 | S1PR1 (0.34) | GAADDR1KCNH2RORCHPGD | |
| SCHEMBL19299809 | 0.88 | RORC (0.34) | MAPTKCNH2RORCHPGDKDM4E | |
| SCHEMBL19283506 | 0.87 | MAPT (0.47) | MAPTKMT2AMEN1GAATSHR | |
| SCHEMBL19299910 | 0.85 | KCNH2 (0.33) | DDR1KCNH2RORCLMNAHTT | |
| SCHEMBL18179545 | 0.84 | KCNH2 (0.36) | DDR1KCNH2RORCLMNA | |
| SCHEMBL19283505 | 0.84 | MAPT (0.37) | MAPTKMT2AMEN1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |