Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 8/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283559 | 0.92 | KCNH2 (0.37) | S1PR1RORCKCNH2 | |
| SCHEMBL19299911 | 0.92 | KCNH2 (0.33) | S1PR1RORCDDR1KCNH2 | |
| SCHEMBL19299912 | 0.91 | KCNH2 (0.35) | RORCDDR1KCNH2 | |
| SCHEMBL19299797 | 0.90 | MAPT (0.36) | RORCDDR1KCNH2ALDH1A1GAA | |
| SCHEMBL19299809 | 0.89 | RORC (0.34) | RORCKCNH2ALDH1A1HPGD | |
| SCHEMBL18050298 | 0.89 | AGPAT2 (0.39) | S1PR1RORCDDR1ACP1AGPAT2 | |
| SCHEMBL19299910 | 0.86 | KCNH2 (0.33) | S1PR1RORCDDR1KCNH2 | |
| SCHEMBL20547209 | 0.84 | KCNH2 (0.32) | RORCKCNH2 | |
| SCHEMBL18072963 | 0.83 | ALDH1A1 (0.32) | S1PR1DDR1AGPAT2ALDH1A1GAA | |
| SCHEMBL18072962 | 0.83 | POLB (0.41) | S1PR1DDR1ACP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10494368-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-03 | — | — | US | disclosed |
| US-10494368-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-03 | — | — | US | disclosed |
| EP-3268361-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-20190040060-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-07 | — | — | US | disclosed |
| US-20190040060-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-07 | — | — | US | disclosed |
| US-10131662-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-20 | — | — | US | disclosed |
| US-20180079748-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079748-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079748-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| EP-3268361-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| WO-2017144341-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-31 | — | — | WO | disclosed |
| WO-2016142327-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016142327-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040060-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | S1PR1 2204/4885RORC 1422/4885DDR1 4577/4885 |
| US-10494368-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | S1PR1 2204/4885RORC 1422/4885DDR1 4577/4885 |
| US-10131662-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | S1PR1 2414/4885RORC 1249/4885DDR1 4590/4885 |
| US-20180079748-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | S1PR1 2414/4885RORC 1249/4885DDR1 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.