Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | STAMBP | O95630 | 1/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 5/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933262 | 0.82 | HDAC6 (0.63) | HDAC6HDAC2HDAC8HDAC1 | |
| SCHEMBL16771926 | 0.80 | BAZ2B (0.47) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL24051970 | 0.80 | HDAC6 (0.67) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL665987 | 0.80 | JUN (0.47) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL7323223 | 0.80 | SMYD3 (0.50) | HDAC6HDAC2SMYD3HDAC1HTT | |
| SCHEMBL185619 | 0.78 | ALDH1A1 (0.58) | HPGDTSHRSMN1; SMN2 | |
| SCHEMBL20757528 | 0.77 | BAZ2B (0.45) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL3952478 | 0.77 | HDAC6 (0.72) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL30445356 | 0.77 | BAZ2B (0.45) | BAZ2BHDAC6HDAC2HDAC8GRM5 | |
| SCHEMBL28134267 | 0.77 | PLK1 (0.50) | BAZ2BHDAC6HDAC2HDAC8GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419974-B1 | PROCESS FOR THE SEPARATION OF ENANTIOMERS OF PIPERAZINE DERIVATIVES | ASCENEURON SA (CH) | 2021-05-05 | — | — | EP | disclosed |
| EP-3419976-B1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON SA (CH) | 2021-04-07 | — | — | EP | disclosed |
| WO-2017144637-A1 | ACID ADDITION SALTS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017144635-A1 | PROCESS FOR THE SEPARATION OF ENANTIOMERS OF PIPERAZINE DERIVATIVES | ASCENEURON S. A. (CH) | 2017-08-31 | — | — | WO | disclosed |