Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20742870 | 0.99 | MAOB (0.33) | MAOB | |
| SCHEMBL19301073 | 0.82 | MAOB (0.37) | MAOB | |
| SCHEMBL19300892 | 0.79 | MAOB (0.37) | MAOB | |
| SCHEMBL19300921 | 0.78 | TACR1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL20742880 | 0.78 | MAOB (0.40) | MAOB | |
| SCHEMBL19300674 | 0.77 | MAOB (0.39) | MAOB | |
| Hydrochloric Acid SCHEMBL20742869 | 0.76 | MAOB (0.41) | MAOB | |
| SCHEMBL18086850 | 0.71 | TDO2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL18063347 | 0.70 | TDO2 (0.40) | — | |
| SCHEMBL19285743 | 0.69 | MMP2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-17 | — | — | US | disclosed |
| US-10836706-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2019-02-21 | — | — | US | disclosed |
| WO-2017147335-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | ABCB11, ABCB1, SLC47A1 | MAOB 950/4885 |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | MAOB 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.