Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301035 | 0.86 | RHOC (0.40) | PNMTMASP2TACR1MEN1KMT2A | |
| SCHEMBL19300696 | 0.77 | HTR2A (0.42) | TACR1KMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL20742874 | 0.76 | HTR2A (0.41) | TACR1KMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL20742873 | 0.76 | HTR2A (0.41) | TACR1KMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL19285632 | 0.76 | HTR2A (0.41) | TACR1KMT2AIDO1 | |
| SCHEMBL183773 | 0.73 | POLB (0.48) | PNMTPOLBLMNAMEN1ALDH1A1 | |
| SCHEMBL2769396 | 0.69 | POLB (0.38) | POLBTACR1LMNAMEN1ALDH1A1 | |
| SCHEMBL625706 | 0.69 | EPHX1 (0.41) | CARM1PRMT6TACR1LMNAALDH1A1 | |
| SCHEMBL27832335 | 0.67 | POLB (0.43) | POLBLMNAMEN1ALDH1A1HTT | |
| SCHEMBL19301087 | 0.67 | OPRM1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147335-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |