Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374566 | 0.77 | ERN1 (0.37) | MAPTKMT2ATDP1MEN1LMNA | |
| SCHEMBL5120598 | 0.70 | TYMS (0.39) | POLBMAPTKMT2AHTTTDP1 | |
| SCHEMBL19301043 | 0.70 | TYMS (0.39) | POLBMAPTKMT2AHTTTDP1 | |
| SCHEMBL5120606 | 0.70 | TYMS (0.39) | POLBMAPTKMT2AHTTTDP1 | |
| SCHEMBL29380022 | 0.70 | TYMS (0.39) | POLBMAPTKMT2AHTTTDP1 | |
| SCHEMBL19300884 | 0.70 | MAPT (0.41) | POLBMAPTKMT2AHTTTDP1 | |
| SCHEMBL18826578 | 0.70 | CA1 (0.38) | MAPTKMT2AHTTMEN1GAA | |
| SCHEMBL23707669 | 0.68 | CES2 (0.50) | MAPTKMT2AHTTTDP1MEN1 | |
| SCHEMBL9140835 | 0.68 | CES2 (0.50) | MAPTKMT2AHTTTDP1MEN1 | |
| SCHEMBL22276494 | 0.66 | CA1 (0.38) | LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017146581-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-08-31 | — | — | WO | disclosed |