Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120606 | 1.00 | TYMS (0.39) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL29380022 | 1.00 | TYMS (0.39) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL5120598 | 1.00 | TYMS (0.39) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL19300884 | 0.84 | MAPT (0.41) | TDP1KDM4EMAPTALDH1A1HTT | |
| SCHEMBL19300899 | 0.84 | MAPT (0.45) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL14386176 | 0.78 | TYMS (0.42) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL14385523 | 0.77 | PTGS2 (0.42) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL19301122 | 0.77 | G6PC1 (0.49) | TYMSTDP1ALOX15KDM4EMAPT | |
| SCHEMBL10432889 | 0.73 | TDP1 (0.46) | TYMSTDP1ALOX15KDM4ECYP1A2 | |
| SCHEMBL20668098 | 0.73 | MAPT (0.34) | TDP1MAPTALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915970-A1 | AROMATIC COMPOUNDS FROM FURANICS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2021-12-01 | — | — | EP | disclosed |
| EP-3419957-B1 | AROMATIC COMPOUNDS FROM FURANICS | TNO (NL) | 2021-09-29 | — | — | EP | disclosed |
| US-10562875-B2 | Aromatic compounds from furanics | NEDERLANDSE ORGANISAITE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-02-18 | — | — | US | disclosed |
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-01-24 | — | — | US | disclosed |
| WO-2017146581-A1 | AROMATIC COMPOUNDS FROM FURANICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023678-A1 | AROMATIC COMPOUNDS FROM FURANICS | PAH, AOX1, TYR | TYMS 387/4885TDP1 1783/4885ALOX15 325/4885 |
| US-10562875-B2 | Aromatic compounds from furanics | PAH, AOX1, TYR | TYMS 387/4885TDP1 1783/4885ALOX15 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.