Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29193469 | 0.80 | NPC1 (0.50) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL1887928 | 0.79 | CYP2C19 (0.50) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL29193474 | 0.79 | SMN1; SMN2 (0.48) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL6231282 | 0.78 | ATM (0.52) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL1640060 | 0.75 | ATM (0.58) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL28333330 | 0.74 | TAAR1 (0.56) | TAAR1CYP1A2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL11708887 | 0.72 | SIGMAR1 (0.46) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL11636072 | 0.71 | TAAR1 (0.44) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL21058251 | 0.71 | ATM (0.52) | NPC1RAB9ATAAR1CYP1A2CYP3A4 | |
| SCHEMBL19334561 | 0.71 | ATM (0.52) | NPC1RAB9ATAAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956219-B2 | Amino acid analogues | Baker IDI Heart and Diabetes (AU) | 2011-06-07 | — | — | US | disclosed |
| EP-1501791-B1 | AMINO ACID ANALOGUES | BAKER MED RES INST (AU) | 2009-01-21 | — | — | EP | disclosed |
| US-20060094902-A1 | Amino acid analogues | BAKER IDI HEART AND DIABETES INSTITUTE HOLDINGS LTD. (AU) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094902-A1 | Amino acid analogues | EDNRB, EDNRA, NOS2 | NPC1 4046/4885RAB9A 1511/4885TAAR1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.