Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303800 | 0.94 | ESR1 (0.37) | ESR1ESR2P4HBALDH1A1MAPT | |
| SCHEMBL19303777 | 0.91 | EGFR (0.38) | EGFRPIM1P4HBALDH1A1MAPT | |
| SCHEMBL5821593 | 0.80 | PTGS2 (0.39) | EGFRPIM1ALDH1A1MAPTMEN1 | |
| SCHEMBL19303801 | 0.80 | KDM4E (0.36) | PIM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19303803 | 0.80 | KDM4E (0.38) | PIM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5820540 | 0.77 | PTGS2 (0.39) | PIM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23159194 | 0.74 | — | — | |
| SCHEMBL19303804 | 0.72 | MAPT (0.41) | PIM1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10494234 | 0.71 | MAPT (0.41) | ALDH1A1MAPTKDM4EHTTNPC1 | |
| SCHEMBL9176608 | 0.70 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421449-B1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVES | UNIV KYOTO (JP) | 2021-03-31 | — | — | EP | disclosed |
| WO-2017145716-A1 | PRODUCTION METHOD FOR 1,1'-BINAPHTHYL DERIVATIVE, AND 1,1'-BINAPHTHYL DERIVATIVE | 国立大学法人京都大学 | 2017-08-31 | — | — | WO | disclosed |