Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | HTRA2 | O43464 | 5/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 5/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14210372 | 0.77 | GJA1 (0.51) | MEN1USP2POLBKMT2AATM | |
| SCHEMBL29974216 | 0.73 | USP2 (0.76) | MEN1USP2POLBKMT2AATM | |
| SCHEMBL13320830 | 0.73 | USP2 (0.76) | MEN1USP2POLBKMT2AATM | |
| SCHEMBL12123525 | 0.72 | ALB (0.60) | MEN1USP2POLBKMT2AFOLH1 | |
| SCHEMBL12675193 | 0.71 | ALB (0.58) | USP2FOLH1ALBHTRA2HTRA1 | |
| SCHEMBL12040501 | 0.71 | ALB (0.57) | USP2FOLH1ALBHTRA2HTRA1 | |
| SCHEMBL14210376 | 0.71 | MEN1 (0.71) | MEN1USP2POLBKMT2AATM | |
| SCHEMBL16153102 | 0.70 | USP2 (0.64) | MEN1USP2POLBKMT2AATM | |
| SCHEMBL18162918 | 0.70 | ALB (0.64) | USP2FOLH1ALBHTRA2HTRA1 | |
| SCHEMBL17307947 | 0.70 | FOLH1 (0.58) | USP2FOLH1ALBHTRA2HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, GUSB | MEN1 3869/4885USP2 1428/4885POLB 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.