Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20330457 | 0.74 | EGFR (0.42) | ALDH1A1MAPTHPGDEGFR | |
| SCHEMBL20169984 | 0.73 | HDAC1 (0.36) | ALDH1A1MAPTHPGDEGFR | |
| SCHEMBL21533354 | 0.72 | RIPK1 (0.44) | CDK5CDK5R1 | |
| SCHEMBL20162136 | 0.70 | HDAC1 (0.41) | ALDH1A1MAPTHPGDEGFR | |
| SCHEMBL19304065 | 0.69 | HDAC3 (0.45) | ALDH1A1HPGD | |
| SCHEMBL20169940 | 0.66 | HDAC1 (0.51) | ALDH1A1MAPTHPGD | |
| SCHEMBL20162176 | 0.65 | TAS2R8 (0.40) | — | |
| SCHEMBL20331324 | 0.65 | CDK5 (0.35) | CDK5CDK5R1 | |
| SCHEMBL21518096 | 0.65 | TAS2R8 (0.43) | CDK5CDK5R1 | |
| SCHEMBL18940396 | 0.64 | JUN (0.40) | CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017146128-A1 | IMIDAZOLYLAMIDE DERIVATIVE | 大日本住友製薬株式会社 | 2017-08-31 | — | — | WO | disclosed |