Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35818 | 0.84 | LTA4H (0.32) | LTA4HTSHR | |
| SCHEMBL573507 | 0.82 | LTA4H (0.30) | LTA4HTSHR | |
| SCHEMBL10699684 | 0.82 | LTA4H (0.30) | LTA4HTSHR | |
| SCHEMBL3296792 | 0.80 | LTA4H (0.57) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL27757762 | 0.79 | LTA4H (0.56) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL2452291 | 0.78 | LTA4H (0.60) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL1931480 | 0.77 | TSHR (0.38) | LTA4HTSHRKMT2A | |
| SCHEMBL19784955 | 0.77 | LTA4H (0.58) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL277910 | 0.76 | — | — | |
| SCHEMBL2498569 | 0.74 | LTA4H (0.55) | LTA4HTSHRNR1H2BAXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637627-B2 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2014-01-28 | — | — | US | disclosed |
| EP-2019106-B1 | (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same | ROHM & HAAS (US) | 2013-11-27 | — | — | EP | disclosed |
| US-8029904-B2 | Aryl (thio)ether aryl polysiloxane composition and methods for making and using same | ROHM AND HAAS COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-7956125-B2 | (Thio)phenoxy phenyl silane compostion and method for making same | ROHM AND HAAS COMPANY (US) | 2011-06-07 | — | — | US | disclosed |
| EP-1927636-B1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | ROHM & HAAS (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20090146324-A1 | Phenoxyphenyl polysiloxane composition and method for making and using same | ROHM AND HAAS COMPANY (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090039313-A1 | (Thio)phenoxy phenyl silane compostion and method for making same | ROHM AND HAAS COMPANY (US) | 2009-02-12 | — | — | US | disclosed |
| EP-2019106-A1 | (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same | Rohm and Haas Company (US) | 2009-01-28 | — | — | EP | disclosed |
| US-20080160323-A1 | Hydrosilation catalysts; for encapsulating semiconductors | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2008-07-03 | — | — | US | disclosed |
| EP-1927636-A1 | Aryl(thio)ether aryl polysiloxane composition and methods for making and using same | Rohm and Haas Company (US) | 2008-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090039313-A1 | (Thio)phenoxy phenyl silane compostion and method for making same | TPMT, TTR, TST | LTA4H 671/4885TSHR 3707/4885NR1H2 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.