SCHEMBL19784955

SCHEMBL19784955

CO[SiH](c1ccc(Oc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.58
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
SRD5A2 P31213 2/20 0.42
CA4 P22748 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PGR P06401 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27757762 0.98 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL15847175 0.83 LTA4H (0.58) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3296792 0.82 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL675766 0.81 CA4 (0.41) LTA4HTSHRSMN1; SMN2CA4CA1
SCHEMBL19985746 0.81 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL1930451 0.77 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3482552 0.76 ACHE (0.43) TSHRSMN1; SMN2HPGDCA4HTT
SCHEMBL2498569 0.76 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL28254838 0.75 LTA4H (0.80) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3893562 0.75 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484896-B1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2023-11-22 EP disclosed
WO-2018011475-A1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2018-01-18 WO disclosed