Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | BRD2 | P25440 | 3/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930420 | 0.90 | L3MBTL1 (0.49) | L3MBTL1BRD4BRD2BRD3ALDH1A1 | |
| SCHEMBL3862847 | 0.85 | L3MBTL1 (0.53) | L3MBTL1BRD4BRD2ALDH1A1PKM | |
| SCHEMBL1929051 | 0.84 | L3MBTL1 (0.51) | L3MBTL1BRD4BRD2ALDH1A1PKM | |
| SCHEMBL1930589 | 0.84 | NR3C1 (0.46) | L3MBTL1BRD4BRD2BRD3ALDH1A1 | |
| SCHEMBL1930375 | 0.83 | ALDH1A1 (0.49) | L3MBTL1BRD4ALDH1A1NPSR1KDM4E | |
| SCHEMBL1928761 | 0.81 | L3MBTL1 (0.57) | L3MBTL1BRD4BRD2ALDH1A1NPSR1 | |
| SCHEMBL1930363 | 0.80 | NPC1 (0.50) | L3MBTL1ALDH1A1NPSR1HTTKDM4E | |
| SCHEMBL1930641 | 0.80 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1PKMNPSR1HTT | |
| SCHEMBL1930307 | 0.80 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1PKMNPSR1HTT | |
| SCHEMBL1930206 | 0.79 | L3MBTL1 (0.48) | L3MBTL1BRD4BRD2BRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956074-B2 | Aryl-isoxazolo-4-yl-oxadiazole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-06-07 | — | — | US | disclosed |