Sugi Predict

Sugi Predict / Compounds / SCHEMBL1930610

SCHEMBL1930610

SCHEMBL1930610

COC(=O)C(C)Oc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.77
▸ L3MBTL1 Q9Y468 1/20 0.77
▸ LTA4H P09960 3/20 0.59
▸ PPARG P37231 2/20 0.57
▸ PPARA Q07869 2/20 0.57
▸ NPC1 O15118 2/20 0.57
▸ RAB9A P51151 2/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ MAOB P27338 1/20 0.55
▸ NR4A1 P22736 1/20 0.54
▸ NR4A2 P43354 1/20 0.54
▸ NR4A3 Q92570 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.53
▸ CYP1A2 P05177 1/20 0.51
▸ PTGS1 P23219 1/20 0.51
▸ SLC6A2 P23975 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ PTGS2 P35354 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51
▸ HIF1A Q16665 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4429923 1.00 LMNA (0.77) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL27566556 0.87 LMNA (0.60) LMNAL3MBTL1LTA4H
SCHEMBL9469655 0.87 LMNA (1.00) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL9621415 0.87 LMNA (1.00) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL9367416 0.87 LMNA (1.00) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL11115557 0.87 LMNA (0.75) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL1547197 0.87 LMNA (0.62) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL5111673 0.86 LMNA (0.74) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL9471057 0.86 LMNA (0.74) LMNAL3MBTL1LTA4HPPARGPPARA
SCHEMBL11511740 0.86 LMNA (0.58) LMNAL3MBTL1LTA4HMAOBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 — — US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 — — US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 — — US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 — — US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 — — US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 — — US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 — — US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 — — US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 — — US disclosed
EP-1761480-B1 MAO-B INHIBITORS HOFFMANN LA ROCHE (CH) 2009-02-18 — — EP disclosed
EP-0544093-A1 4-Carboxy-2-aryloxyphenoxyalkyl substituted heterocycles useful as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1993-06-02 — — EP disclosed
US-5213606-A 4-CARBOXY-2-ARYLOXYPHENOXYALKYL SUBSTITUTED HETEROCYCLES USEFUL AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1993-05-25 — — US disclosed
US-4609396-A GRASSES IN BROADLEAF CROPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-09-02 — — US disclosed
EP-0042750-B1 QUINOXALINYLOXY ETHERS AS SELECTIVE WEED CONTROL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-30 — — EP disclosed
US-4368068-A PRE- AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-11 — — US disclosed
EP-0042750-A2 Quinoxalinyloxy ethers as selective weed control agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-30 — — EP disclosed
US-4205978-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxyalkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds ISHIHARA SANGYO KAISHA, LTD. (JP) 1980-06-03 — — US disclosed
US-4193790-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxy-alkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds Ishihara Sangyo Kabushiki Kaisha Ltd. (JP) 1980-03-18 — — US disclosed
US-4183743-A IN CROPS OF PLANTS SUCH AS CEREALS ISHIHARA SANGYO KAISHA LTD. (JP) 1980-01-15 — — US disclosed
US-4106925-A PREEMERGENT AND POSTEMERGENT ISHIHARA SANGYO KAISHA LTD. (JP) 1978-08-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM HAO2, HCAR2, HAAO LMNA 3575/4885L3MBTL1 2389/4885LTA4H 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.