SCHEMBL1930643

SCHEMBL1930643

COc1ccc2c(c1)Oc1cc(OC)ccc1C21OC(=O)c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.74
MAPT P10636 6/20 0.73
LMNA P02545 6/20 0.73
MEN1 O00255 5/20 0.73
KMT2A Q03164 5/20 0.73
HTT P42858 2/20 0.73
USP2 O75604 2/20 0.73
ALDH1A1 P00352 2/20 0.73
FTO Q9C0B1 6/20 0.64
TDP1 Q9NUW8 4/20 0.64
RECQL P46063 2/20 0.64
BLM P54132 2/20 0.64
PRMT1 Q99873 2/20 0.64
ACE2 Q9BYF1 2/20 0.64
CYP2C19 P33261 2/20 0.64
HPGD P15428 1/20 0.64
SMAD3 P84022 1/20 0.64
GSTP1 P09211 1/20 0.52
NPSR1 Q6W5P4 3/20 0.50
POLB P06746 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386324 1.00 CYP3A4 (0.74) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL18363816 0.94 CYP3A4 (0.67) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL6622095 0.93 FTO (0.79) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL17037008 0.93 CYP3A4 (0.65) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL29469741 0.93 FTO (0.79) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL14852621 0.92 MAPT (0.69) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL23642903 0.91 CYP3A4 (0.63) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL20362462 0.91 CYP3A4 (0.63) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL21075909 0.91 MAPT (0.91) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL8372869 0.89 MAPT (0.64) CYP3A4MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116088-A1 THERMOCHROMISM INDICATOR 江苏集萃智能液晶科技有限公司 2023-06-29 WO claimed
CN-112581856-B Temperature indicating label 苏州和萃新材料有限公司 2022-07-19 CN claimed
CN-114353991-A Temperature-sensitive color-changing indicator 江苏集萃智能液晶科技有限公司 2022-04-15 CN claimed
CN-114015432-A Reversible thermochromic material capable of reducing temperature, decoloring, raising temperature and developing color and preparation method thereof 北京服装学院 2022-02-08 CN claimed
CN-113789086-A High-temperature color-changing ink and label 江苏集萃智能液晶科技有限公司 2021-12-14 CN claimed
CN-113390521-A Temperature indicating device 江苏集萃智能液晶科技有限公司 2021-09-14 CN claimed
CN-213740341-U Inkless printing paper 湖南鼎一致远科技发展有限公司 2021-07-20 CN claimed
CN-112652230-A Irreversible temperature sensing timing label 苏州和萃新材料有限公司 2021-04-13 CN claimed
CN-112581856-A Temperature indicating label 苏州和萃新材料有限公司 2021-03-30 CN claimed
CN-112577626-A Timing temperature indicating label 苏州和萃新材料有限公司 2021-03-30 CN claimed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP claimed
US-12202994-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2025-01-21 US disclosed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US disclosed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN disclosed
US-11920047-B2 Method for preparing thermochromic water-based gel ink compositions, and thermochromic water-based gel ink compositions thereof SOCIéTé BIC (FR) 2024-03-05 US disclosed
EP-1263607-A1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORPORATION (US) 2002-12-11 EP disclosed
WO-2002024629-A1 ZWITTERIONIC TACHYKININ RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2002-03-28 WO disclosed
US-20010043239-A1 Thermal transfer recording system MOROOD INTERNATIONAL, SPC (SA) 2001-11-22 US disclosed
WO-2001056805-A1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORPORATION (US) 2001-08-09 WO disclosed
US-4681791-A XANTHENE DYES PILOT INK CO., LTD. (JP) 1987-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 CYP3A4 2565/4885MAPT 333/4885LMNA 3184/4885
US-12202994-B2 Thermochromic pigment compositions TYR, MITF, MC1R CYP3A4 2506/4885MAPT 357/4885LMNA 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.