Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10445033 | 0.98 | KDM4E (0.43) | SLC6A4SLC6A2SLC6A3LTA4HALDH1A1 | |
| Methylethylamine SCHEMBL4595057 | 0.80 | ALDH1A1 (0.38) | SLC6A4SLC6A2SLC6A3ALDH1A1CYP3A4 | |
| SCHEMBL8749936 | 0.80 | TSHR (0.45) | SLC6A4SLC6A2SLC6A3ALDH1A1KDM4E | |
| SCHEMBL7741253 | 0.80 | ALDH1A1 (0.38) | SLC6A4SLC6A2ALDH1A1KDM4EKCNH2 | |
| SCHEMBL23252534 | 0.80 | TAAR1 (0.53) | SLC6A2ALDH1A1KDM4ECYP3A4HTR2A | |
| SCHEMBL50299 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL16299849 | 0.79 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3LTA4HALDH1A1 | |
| Dimethylamine SCHEMBL8062717 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKCNH2KMT2A | |
| SCHEMBL27380622 | 0.79 | LMNA (0.48) | SLC6A4SLC6A2SLC6A3LTA4HALDH1A1 | |
| SCHEMBL11032962 | 0.79 | MEN1 (0.40) | LTA4HALDH1A1KDM4EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984035-A2 | MEDICAL DEVICES HAVING TEXTURED SURFACES | Medtronic, Inc. (US) | 2008-10-29 | — | — | EP | claimed |
| US-20070225785-A1 | MEDICAL DEVICES HAVING TEXTURED SURFACES | MEDTRONIC, INC. (US) | 2007-09-27 | — | — | US | claimed |
| WO-2007095549-A2 | MEDICAL DEVICES HAVING TEXTURED SURFACES | MEDTRONIC, INC. (US) | 2007-08-23 | — | — | WO | claimed |
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11661431-B2 | Thienopyrrole compounds | GILEAD SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| WO-2023004266-A1 | IMMUNOCONJUGATES AND METHODS | RECURIUM IP HOLDINGS, LLC (US) | 2023-01-26 | — | — | WO | disclosed |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2022-12-08 | — | — | US | disclosed |
| WO-2017102784-A9 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2017185324-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN OLEFIN DISPROPORTIONATION REACTIONS | XIA, LING (CN) | 2017-11-02 | — | — | WO | disclosed |
| WO-2017102784-A1 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2017-06-22 | — | — | WO | disclosed |
| US-9206167-B2 | Piperazine-substituted benzothiophenes for treatment of mental disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20140163039-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-7955512-B2 | Medical devices having textured surfaces | MEDTRONIC, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| WO-2010148381-A2 | GROUP IV OLEFIN POLYMERIZATION CATALYSTS AND POLYMERIZATION METHODS | CORNELL UNIVERSITY (US) | 2010-12-23 | — | — | WO | disclosed |
| EP-1984035-A2 | MEDICAL DEVICES HAVING TEXTURED SURFACES | Medtronic, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070225785-A1 | MEDICAL DEVICES HAVING TEXTURED SURFACES | MEDTRONIC, INC. (US) | 2007-09-27 | — | — | US | disclosed |
| WO-2007095549-A2 | MEDICAL DEVICES HAVING TEXTURED SURFACES | MEDTRONIC, INC. (US) | 2007-08-23 | — | — | WO | disclosed |
| EP-0389928-A2 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| US-4734351-A | DISPERSION OF POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0091039-A2 | Anti-fouling agent | Nitto Kasei Co., Ltd. (JP) | 1983-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365594-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | SLC6A4 2687/4885SLC6A2 2341/4885SLC6A3 2578/4885 |
| US-20140163039-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | GRIN2C, TPH1, HTR2C | SLC6A4 41/4885SLC6A2 94/4885SLC6A3 27/4885 |
| US-11661431-B2 | Thienopyrrole compounds | SSB, TPMT, LCP2 | SLC6A4 2687/4885SLC6A2 2341/4885SLC6A3 2578/4885 |
| US-20220389034-A1 | THIENOPYRROLE COMPOUNDS | SSB, TPMT, LCP2 | SLC6A4 2687/4885SLC6A2 2341/4885SLC6A3 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.