Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.98 |
| ▸ | USP2 | O75604 | 3/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.98 |
| ▸ | GAA | P10253 | 2/20 | 0.98 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tenoxicam SCHEMBL25343 | 0.99 | PTGS1 (1.00) | PTGS1KDM4EUSP2CYP2C9GAA | |
| Tenoxicam SCHEMBL1683529 | 0.94 | PTGS1 (0.90) | PTGS1KDM4EUSP2CYP2C9GAA | |
| Piroxicam SCHEMBL6846290 | 0.93 | PTGS1 (0.89) | PTGS1KDM4EUSP2CYP2C9GAA | |
| Lornoxicam SCHEMBL4745029 | 0.90 | ABCB11 (0.88) | PTGS1KDM4EUSP2CYP2C9GAA | |
| SCHEMBL14628817 | 0.88 | PTGS1 (0.80) | PTGS1KDM4EUSP2CYP2C9GAA | |
| SCHEMBL11473095 | 0.87 | PTGS1 (0.78) | PTGS1KDM4EUSP2CYP2C9GAA | |
| SCHEMBL13777309 | 0.86 | PTGS1 (0.77) | PTGS1KDM4EUSP2CYP2C9GAA | |
| Piroxicam SCHEMBL9114300 | 0.85 | PTGS1 (0.74) | PTGS1KDM4EUSP2CYP2C9GAA | |
| Piroxicam SCHEMBL1444687 | 0.85 | ABCB11 (0.79) | PTGS1KDM4EUSP2CYP2C9GAA | |
| SCHEMBL11485261 | 0.85 | PTGS1 (0.76) | PTGS1KDM4EUSP2CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361897-A1 | ENANTIOSELECTIVE DESTRUCTION OF CHIRAL MOLECULES | NATIONAL SCIENCE FOUNDATION | 2020-11-19 | — | — | US | disclosed |
| US-10611752-B2 | Enantioselective destruction of chiral molecules | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20170253538-A1 | ENANTIOSELECTIVE DESTRUCTION OF CHIRAL MOLECULES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2017-09-07 | — | — | US | disclosed |