Tenoxicam

Tenoxicam

SCHEMBL25343

CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 1.00
KDM4E B2RXH2 3/20 1.00
USP2 O75604 3/20 1.00
CYP2C9 P11712 2/20 1.00
GAA P10253 1/20 1.00
ABCB11 O95342 2/20 0.70
POLB P06746 1/20 0.70
PTGS2 P35354 4/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
ALOX15 P16050 1/20 0.69
NFKB1 P19838 1/20 0.69
CYP2C19 P33261 1/20 0.69
BLM P54132 1/20 0.69
SLC22A6 Q4U2R8 1/20 0.69
SLC22A8 Q8TCC7 1/20 0.69
MAPK1 P28482 1/20 0.68
HTR1A P08908 1/20 0.49
LMNA P02545 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tenoxicam SCHEMBL19307296 0.99 PTGS1 (0.98) PTGS1KDM4EUSP2CYP2C9GAA
Tenoxicam SCHEMBL1683529 0.95 PTGS1 (0.90) PTGS1KDM4EUSP2CYP2C9GAA
Piroxicam SCHEMBL6846290 0.94 PTGS1 (0.89) PTGS1KDM4EUSP2CYP2C9GAA
Lornoxicam SCHEMBL4745029 0.91 ABCB11 (0.88) PTGS1KDM4EUSP2CYP2C9GAA
SCHEMBL14628817 0.89 PTGS1 (0.80) PTGS1KDM4EUSP2CYP2C9GAA
SCHEMBL11473095 0.88 PTGS1 (0.78) PTGS1KDM4EUSP2CYP2C9GAA
SCHEMBL13777309 0.87 PTGS1 (0.77) PTGS1KDM4EUSP2CYP2C9GAA
Piroxicam SCHEMBL9114300 0.86 PTGS1 (0.74) PTGS1KDM4EUSP2CYP2C9GAA
Piroxicam SCHEMBL1444687 0.86 ABCB11 (0.79) PTGS1KDM4EUSP2CYP2C9GAA
SCHEMBL11485261 0.86 PTGS1 (0.76) PTGS1KDM4EUSP2CYP2C9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 37316 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
EP-3841097-B1 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) 2026-05-20 EP claimed
US-20260130928-A1 COMBINATION OF AKR1C3 ACTIVATED ANTICANCER PRODRUG COMPOUND AND ANALGESIC DRUG FOR TREATING CANCER PATIENTS ACCOMPANIED BY PAIN ASCENTAWITS PHARMACEUTICALS LTD (CN) 2026-05-14 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-12605432-B2 Combinations for antigen based therapy DIAMYD MEDICAL AB (SE) 2026-04-21 US claimed
US-20260069532-A1 METHOD FOR MORSELIZING AND/OR TARGETING PHARMACEUTICALLY ACTIVE PRINCIPLES TO SYNOVIAL TISSUE MEDINCELL S.A. (FR) 2026-03-12 US claimed
US-12558309-B2 Method for morselizing and/or targeting pharmaceutically active principles to synovial tissue MEDINCELL S.A. (FR) 2026-02-24 US claimed
US-12534571-B2 Amphiphilic block copolymer, preparation method thereof and nanomicelle drug-loading system SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2026-01-27 US claimed
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 US claimed
EP-4665315-A1 METHODS OF PREPARATION OF ZINGERONE, COMPOSITIONS COMPRISING ZINGERONE, AND USES THEREFOR Evithe Limited (NZ) 2025-12-24 EP claimed
EP-0270316-A2 Topical compositions comprising 1-substituted imidazoles and NSAIDs for treatment of acne PFIZER INC. (US) 1988-06-08 EP claimed
US-4748174-A NONSTEROIDAL ANTIINFLAMMATORY AND ANALGESIC DRUGS THERAPICON S.R.L. (IT) 1988-05-31 US claimed
WO-1987007506-A1 METHODS AND COMPOSITIONS USING LIPOSOME-ENCAPSULATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS THE LIPOSOME COMPANY, INC. (US) 1987-12-17 WO claimed
EP-0249561-A2 Compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs THE LIPOSOME COMPANY, INC. (US) 1987-12-16 EP claimed
US-4687766-A MIXTURE OF OXICAM DERIVATIVES WITH PHOSPHOLIPID A. NATTERMAN & CIE, GMBH (DE) 1987-08-18 US claimed
US-4636498-A OXICAMS, ANTIULCER, ANTISECRETORY 2-GUANIDINO-4-(4-IMIDAZOLYL) THIAZOLES PFIZER INC. (US) 1987-01-13 US claimed
EP-0196434-A1 Process for the preparation of a composition based on a divided substance with a slight hydrosolubility SOCIETE DES PRODUITS NESTLE S.A. (CH) 1986-10-08 EP claimed
CN-86101476-A Based on the preparation of compositions of forming by the fine separation active principle of low aqueous solubility 1986-09-17 CN claimed
EP-0178121-A2 Improved formulation of antiinflammatory drugs PFIZER INC. (US) 1986-04-16 EP claimed
EP-0147735-A2 Pharmaceutical preparation for the therapeutic treatment of rheumatic diseases A. Nattermann & Cie. GmbH (DE) 1985-07-10 EP claimed