Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15276858 | 0.80 | SMN1; SMN2 (0.54) | KMT2ALMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18948489 | 0.76 | ALDH1A1 (0.63) | KMT2ALMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL15076753 | 0.76 | CNR1 (0.58) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15276854 | 0.74 | SMN1; SMN2 (0.57) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5252678 | 0.73 | LMNA (0.63) | KMT2ALMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL15276860 | 0.71 | MEN1 (0.58) | KMT2ASMN1; SMN2ALDH1A1MEN1CNR1 | |
| SCHEMBL21800640 | 0.69 | SLC13A5 (0.75) | KMT2ASLC13A5ALDH1A1PKMTSHR | |
| SCHEMBL21613701 | 0.68 | MBTD1 (0.52) | KMT2ASMN1; SMN2ALDH1A1MEN1HTR2A | |
| SCHEMBL17014208 | 0.68 | MBTD1 (0.52) | KMT2ALMNANPSR1ALDH1A1PKM | |
| SCHEMBL17479278 | 0.68 | MEN1 (0.54) | KMT2ALMNASMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751857-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-09-05 | — | — | US | disclosed |