Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.45 |
| ▸ | THRA | P10827 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308103 | 0.90 | THRB (0.40) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL12584488 | 0.83 | THRB (0.47) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL12584474 | 0.82 | THRB (0.62) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL18556479 | 0.78 | THRB (0.58) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL12584490 | 0.77 | THRB (0.47) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL13949736 | 0.76 | THRB (0.64) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL13949734 | 0.74 | THRB (0.41) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL12584529 | 0.71 | THRB (0.51) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL13949735 | 0.70 | THRB (0.41) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL17612147 | 0.70 | THRB (0.42) | THRBTHRAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9750709-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof | NANOPHARMACEUTICALS LLC (US) | 2017-09-05 | — | — | US | disclosed |