Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12650704 | 0.81 | NAAA (0.50) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL18685664 | 0.79 | TSHR (0.53) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL19002780 | 0.79 | NAAA (0.54) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL517349 | 0.78 | NAAA (0.73) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL8690270 | 0.78 | NAAA (0.73) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL3184451 | 0.78 | NAAA (0.66) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL28065417 | 0.77 | NAAA (0.71) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL8140520 | 0.76 | NAAA (0.70) | NAAAEPHX1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL2639022 | 0.75 | NAAA (0.86) | NAAAEPHX1SMN1; SMN2HSD17B10KEAP1 | |
| SCHEMBL6359440 | 0.75 | NAAA (0.86) | NAAAEPHX1SMN1; SMN2HSD17B10KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752153-B2 | Alkynyl-derivatized cap analogs, preparation and uses thereof | Life Technologies Corporation (US) | 2017-09-05 | — | — | US | disclosed |