SCHEMBL19309

SCHEMBL19309

C=CC=CC(C=Cc1ccccc1)=CC#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
MAPT P10636 3/20 0.39
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39
ALDH1A1 P00352 3/20 0.39
PLIN1 O60240 2/20 0.39
RECQL P46063 2/20 0.39
PLIN5 Q00G26 2/20 0.39
ABHD5 Q8WTS1 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
TNKS O95271 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL8991739 0.98 LMNA (0.38) LMNAMAPTHDAC3HDAC4HDAC1
Acrylonitrile SCHEMBL11458975 0.97 KDM4E (0.37) LMNAMAPTHDAC3HDAC4HDAC1
Acrylonitrile SCHEMBL6375424 0.97 KDM4E (0.37) LMNAMAPTHDAC3HDAC4HDAC1
Styrene SCHEMBL7168836 0.95 ALDH1A1 (0.41) LMNAMAPTHDAC3HDAC4HDAC1
Bicarbonate SCHEMBL278424 0.95 MAPT (0.43) LMNAMAPTHDAC3HDAC4HDAC1
Vinyl Chloride SCHEMBL10482333 0.95 LMNA (0.36) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL6762042 0.94 MAOB (0.40) LMNAMAPTHDAC3HDAC4HDAC1
Phosphoric Acid SCHEMBL4366545 0.94 LMNA (0.39) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL11206156 0.92 LMNA (0.33) LMNAMAPTHDAC3HDAC4HDAC1
SCHEMBL5141317 0.92 HDAC3 (0.47) LMNAMAPTHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 134055 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
US-6390375-B1 None US claimed
US-20260146144-A1 SYNERGISTIC STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2026-05-28 US claimed
US-20260145038-A1 GOLF CLUB HEAD WITH FILLED CAVITY AND CHAMBER WITH PNEUMATIC INSERT KARSTEN MANUFACTURING CORPORATION (US) 2026-05-28 US claimed
US-20260144320-A1 Shock Absorber Assembly, Personal Protective Equipment Therewith, Deformable Element For And Method Of Retrofitting Of Such An Assembly 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-28 US claimed
US-20260146154-A1 HYDROSTABLE THERMOPLASTIC COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US claimed
US-20260145143-A1 Gas Infusion Apparatus and Method of Making Sauceman, Shane (US) 2026-05-28 US claimed
EP-3489303-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2026-05-27 EP claimed
EP-4747302-A2 REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS Nanocore ApS (DK) 2026-05-27 EP claimed
EP-4156400-B1 SEPARATOR FOR SECONDARY BATTERY LG ENERGY SOLUTION LTD (KR) 2026-05-27 EP claimed
US-3953658-A VAPOR DEPOSITION HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-27 US claimed
US-3950255-A WOVEN FABRICS, SOLUBILITY DAICEL LTD. (JA) 1976-04-13 US claimed
US-3947367-A Hydroxy acid heat stabilizers for ABS resins lubricated with ethylenediamine bis-stearamide GLYCO CHEMICALS, INC. (US) 1976-03-30 US claimed
US-3945847-A GRAPHITE UNION CARBIDE CORPORATION (US) 1976-03-23 US claimed
US-3945974-A ZINC OXIDE N L INDUSTRIES, INC. (US) 1976-03-23 US claimed
US-3945844-A Electrochemical cell UNITED AIRCRAFT CORPORATION (US) 1976-03-23 US claimed
US-3936417-A CHLORINATED POLYETHYLENE, ZINC OR TITANIUM OXIDE FILLER GRANDVIEW INDUSTRIES, LIMITED (CA) 1976-02-03 US claimed
US-3934749-A Plastic container POLYSAR PLASTICS, INC. (US) 1976-01-27 US claimed
US-3931836-A Laminated polymeric articles and process for the production thereof JOHNS-MANVILLE CORPORATION (US) 1976-01-13 US claimed
US-3930419-A Casing for shafts and cables GENERAL ELECTRIC COMPANY (US) 1976-01-06 US claimed