Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19309 | 0.94 | LMNA (0.39) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Bicarbonate SCHEMBL278424 | 0.93 | MAPT (0.43) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Butadiene SCHEMBL8991739 | 0.93 | LMNA (0.38) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Acrylonitrile SCHEMBL6375424 | 0.91 | KDM4E (0.37) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Acrylonitrile SCHEMBL11458975 | 0.91 | KDM4E (0.37) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Vinyl Chloride SCHEMBL10482333 | 0.90 | LMNA (0.36) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| Styrene SCHEMBL7168836 | 0.90 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL11808838 | 0.90 | GLA (0.35) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL5141317 | 0.89 | HDAC3 (0.47) | LMNAMAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL6762042 | 0.89 | MAOB (0.40) | LMNAMAPTALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494614-B2 | Method of manufacture of porous inorganic structures | PILLIAR ROBERT M | 2009-02-24 | — | — | US | disclosed |
| EP-1521730-A2 | METHOD OF MANUFACTURE OF POROUS INORGANIC STRUCTURES AND INFILTRATION WITH ORGANIC POLYMERS | Pilliar, Robert M. (CA) | 2005-04-13 | — | — | EP | disclosed |
| US-20040043051-A1 | Method of manufacture of porous inorganic structures and infiltration with organic polymers | PILLIAR ROBERT M (CA) | 2004-03-04 | — | — | US | disclosed |
| WO-2004007399-A2 | METHOD OF MANUFACTURE OF POROUS INORGANIC STRUCTURES AND INFILTRATION WITH ORGANIC POLYMERS | PILLIAR ROBERT M (CA) | 2004-01-22 | — | — | WO | disclosed |