Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 16/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989963 | 0.86 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2F2HDAC6HTR2C | |
| SCHEMBL6606024 | 0.82 | F2 (0.61) | F2MASP2HTR2C | |
| SCHEMBL15624767 | 0.82 | F2 (0.57) | F2 | |
| SCHEMBL172079 | 0.80 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL13746002 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2HDAC6HTR2C | |
| SCHEMBL13745651 | 0.80 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL4037264 | 0.80 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL526330 | 0.80 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL8809131 | 0.79 | HTR2C (0.64) | F2MASP2HTR2C | |
| Hydrochloric Acid SCHEMBL6479155 | 0.79 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752149-B2 | Matriptase inhibitors and uses thereof against orthomyxoviridae infections | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2017-09-05 | — | — | US | disclosed |