Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547446 | 0.82 | MAPT (0.48) | ALDH1A1MAPTKMT2AGAAPOLB | |
| SCHEMBL12406349 | 0.79 | PKM (0.38) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL22340249 | 0.79 | HPGD (0.37) | ALDH1A1POLBNPC1USP2RAB9A | |
| SCHEMBL15372143 | 0.79 | HPGD (0.41) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL20195364 | 0.78 | KCNH2 (0.35) | ALDH1A1GAARECQLTSHRCYP3A4 | |
| SCHEMBL14538645 | 0.78 | KMT2A (0.39) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL22643223 | 0.78 | HPGD (0.36) | ALDH1A1MAPTPOLBKDM4ENPC1 | |
| SCHEMBL12169282 | 0.78 | KMT2A (0.39) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL15372136 | 0.77 | HPGD (0.40) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL20919908 | 0.77 | KCNH2 (0.38) | ALDH1A1KMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077386-B1 | BENZHYDRYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | CHIESI FARM SPA (IT) | 2017-09-06 | — | — | EP | disclosed |