Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22643223 | 0.98 | HPGD (0.36) | HPGDSMN1; SMN2NPC1RAB9ASIGMAR1 | |
| SCHEMBL18828601 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL3773093 | 0.81 | DPP4 (0.34) | — | |
| SCHEMBL12406349 | 0.79 | PKM (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL19313630 | 0.79 | ALDH1A1 (0.41) | NPC1RAB9ASIGMAR1ALDH1A1USP2 | |
| SCHEMBL20195364 | 0.78 | KCNH2 (0.35) | HPGDSIGMAR1ALDH1A1 | |
| SCHEMBL6595771 | 0.78 | DUSP3 (0.49) | HPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3785904 | 0.78 | DPP4 (0.33) | HPGDALDH1A1LMNA | |
| SCHEMBL14538645 | 0.78 | KMT2A (0.39) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL12169282 | 0.78 | KMT2A (0.39) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163689-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-13 | — | — | WO | disclosed |