Sugi Predict

Sugi Predict / Compounds / SCHEMBL19320189

SCHEMBL19320189

SCHEMBL19320189

Brc1cccc(-n2c3ccccc3c3ccncc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ DYRK1A Q13627 2/20 0.38
▸ CDK4 P11802 2/20 0.37
▸ CDK6 Q00534 2/20 0.37
▸ MAOA P21397 4/20 0.37
▸ MAOB P27338 4/20 0.37
▸ ACHE P22303 1/20 0.37
▸ EGFR P00533 1/20 0.36
▸ DCTPP1 Q9H773 1/20 0.36
▸ GSK3B P49841 2/20 0.35
▸ GSK3A P49840 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ METAP2 P50579 1/20 0.35
▸ MAT2A P31153 1/20 0.35
▸ MGLL Q99685 1/20 0.35
▸ CHUK O15111 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518793 0.91 CDK4 (0.37) MEN1KMT2ADYRK1ACDK4CDK6
SCHEMBL966613 0.91 MAOA (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL29501298 0.91 CDK4 (0.37) MEN1KMT2ADYRK1ACDK4CDK6
SCHEMBL22139282 0.89 KDM4E (0.52) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL11910140 0.89 KDM4E (0.52) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL804490 0.88 KDM4E (0.43) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL258888 0.86 KDM4E (0.59) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL29514822 0.86 KDM4E (0.59) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL16356755 0.85 MAOA (0.49) KDM4EATML3MBTL1DYRK1ACDK4
SCHEMBL5031115 0.85 KDM4E (0.47) KDM4EATML3MBTL1DYRK1ACDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 — — US disclosed
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 — — US disclosed
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 — — US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 — — US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME ORAI2, VDAC2, PIEZO1 KDM4E 594/4885ATM 2903/4885L3MBTL1 783/4885
US-11723269-B2 Organic electroluminescent materials and devices PUF60, CD99, DDT KDM4E 3163/4885ATM 3362/4885L3MBTL1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.