SCHEMBL19320197

SCHEMBL19320197

Brc1ccc2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 1/20 0.60
ATM Q13315 3/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
WHR1 P49842 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 5/20 0.52
RXFP1 Q9HBX9 3/20 0.52
THRB P10828 1/20 0.52
POLB P06746 1/20 0.51
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
CYP1A1 P04798 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP1B1 Q16678 1/20 0.49
PPARG P37231 1/20 0.48
NCOR2 Q9Y618 1/20 0.48
DCLK1 O15075 1/20 0.47
PRKD3 O94806 1/20 0.47
MAP4K4 O95819 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18455642 0.97 PRNP (0.63) PRNPATMKMT2AMEN1WHR1
SCHEMBL29137767 0.86 WHR1 (0.54) PRNPATMKMT2AMEN1WHR1
SCHEMBL15003695 0.85 MEN1 (0.69) ATMKMT2AMEN1WHR1MAPT
SCHEMBL19320195 0.85 MEN1 (0.69) ATMKMT2AMEN1WHR1MAPT
SCHEMBL22603326 0.85 MEN1 (0.69) ATMKMT2AMEN1WHR1MAPT
SCHEMBL23352770 0.85 MEN1 (0.69) ATMKMT2AMEN1WHR1MAPT
SCHEMBL31683846 0.85 MEN1 (0.69) ATMKMT2AMEN1WHR1MAPT
SCHEMBL18455539 0.85 KMT2A (0.55) PRNPATMKMT2AMEN1WHR1
SCHEMBL21174579 0.84 MEN1 (0.55) PRNPATMKMT2AMEN1WHR1
SCHEMBL9889191 0.83 MEN1 (0.71) ATMKMT2AMEN1WHR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME ORAI2, VDAC2, PIEZO1 PRNP 2296/4885ATM 2903/4885KMT2A 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.