Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.71 |
| ▸ | CRHBP | P24387 | 1/20 | 0.71 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | P4HB | P07237 | 1/20 | 0.66 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082293 | 1.00 | TLR9 (0.71) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL1821464 | 0.90 | TLR9 (0.58) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL12446433 | 0.90 | TLR9 (0.58) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL2911444 | 0.89 | TLR9 (0.87) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL2911445 | 0.89 | TLR9 (0.87) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL25185026 | 0.83 | CRHBP (1.00) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL25190978 | 0.83 | MAPT (0.79) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL5950048 | 0.83 | MAPT (0.77) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL25200425 | 0.83 | CRHBP (1.00) | TLR9CRHBPCRHR2MAPTKMT2A | |
| SCHEMBL5950050 | 0.83 | MAPT (0.77) | TLR9CRHBPCRHR2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150168605-A1 | NANOSTRUCTURED CONTACT LENSES AND RELATED OPHTHALMIC MATERIALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-06-18 | — | — | US | disclosed |
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120309761-A1 | FAST-RESPONSE PHOTOCHROMIC NANOSTRUCTURED CONTACT LENSES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-12-06 | — | — | US | disclosed |
| EP-1644330-B1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIV MARYLAND (US) | 2011-08-17 | — | — | EP | disclosed |
| US-20110136929-A1 | TRAPPING GLUCOSE PROBE IN PORES OF POLYMER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-09 | — | — | US | disclosed |
| US-20100297016-A1 | QUARTERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2010-11-25 | — | — | US | disclosed |
| US-7718804-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2010-05-18 | — | — | US | disclosed |
| EP-1644330-A4 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIV MARYLAND BIOTECH INST (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | GEDDES, CHRIS, DR. | 2007-01-25 | — | — | US | disclosed |
| EP-1644330-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005000109-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297016-A1 | QUARTERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | TLR9 3219/4885CRHBP 2442/4885CRHR2 4009/4885 |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | TLR9 3117/4885CRHBP 2323/4885CRHR2 3710/4885 |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | SLC5A1, NISCH, SLC5A2 | TLR9 3117/4885CRHBP 2323/4885CRHR2 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.