Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | CASP3 | P42574 | 2/20 | 0.74 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.74 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.74 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.74 |
| ▸ | F3 | P13726 | 2/20 | 0.74 |
| ▸ | MAOB | P27338 | 5/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045509 | 1.00 | CRHBP (1.00) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL25185026 | 1.00 | CRHBP (1.00) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL3045501 | 1.00 | CRHBP (1.00) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL25200423 | 1.00 | CRHBP (1.00) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL2911445 | 0.93 | TLR9 (0.87) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL2911444 | 0.93 | TLR9 (0.87) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL25205299 | 0.87 | MAPT (0.79) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL482965 | 0.87 | MAPT (0.77) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL5950048 | 0.87 | MAPT (0.77) | CRHBPCRHR2TLR9MAPTRAB9A | |
| SCHEMBL25190978 | 0.87 | MAPT (0.79) | CRHBPCRHR2TLR9MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | CRHBP 1697/4885CRHR2 3801/4885TLR9 4430/4885 |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | CRHBP 1079/4885CRHR2 3714/4885TLR9 4548/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | CRHBP 1079/4885CRHR2 3714/4885TLR9 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.