Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166821 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL27487560 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL194462 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL5460294 | 0.75 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL1735497 | 0.71 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL2881066 | 0.70 | CNR2 (0.63) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL6494047 | 0.69 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| Hydrochloric Acid SCHEMBL8046149 | 0.69 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| Hydrochloric Acid SCHEMBL8046146 | 0.69 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1TDP1CYP3A4GFER | |
| SCHEMBL2868656 | 0.68 | HRH3 (0.50) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239137-B1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | DU PONT (US) | 2019-02-13 | — | — | EP | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| EP-3239137-A1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9604962-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150291556-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CORTEVA AGRISCIENCE LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291578-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CORTEVA AGRISCIENCE LLC | 2015-10-15 | — | — | US | disclosed |
| US-9090604-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-28 | — | — | US | disclosed |
| US-20140081027-A1 | FUNGICIDAL AZOCYCLIC AMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8642634-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-04 | — | — | US | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-8420673-B2 | Fungicidal amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-16 | — | — | US | disclosed |
| US-8349870-B2 | Fungicidal hetercyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2402332-A2 | Fungicidal heterocyclic compounds | E.I. Du Pont De Nemours And Company (US) | 2012-01-04 | — | — | EP | disclosed |
| US-20100292275-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100286147-A1 | FUNGICIDAL AMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| US-20100004288-A1 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291556-A1 | FUNGICIDAL AZOCYCLIC AMIDES | ARG1, NAT1, CHRM1 | ALDH1A1 999/4885L3MBTL1 1495/4885TDP1 1402/4885 |
| US-20100286147-A1 | FUNGICIDAL AMIDES | NAT1, NOX1, CBR1 | ALDH1A1 595/4885L3MBTL1 1068/4885TDP1 1362/4885 |
| US-20100292275-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, CBR1, NOX1 | ALDH1A1 506/4885L3MBTL1 1464/4885TDP1 1133/4885 |
| US-20140081027-A1 | FUNGICIDAL AZOCYCLIC AMIDES | ARG1, NAT1, CHRM1 | ALDH1A1 999/4885L3MBTL1 1495/4885TDP1 1402/4885 |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | ALDH1A1 440/4885L3MBTL1 769/4885TDP1 960/4885 |
| US-20090156592-A1 | Fungicidal Azocyclic Amides | ARG1, NAT1, CHRM1 | ALDH1A1 999/4885L3MBTL1 1495/4885TDP1 1402/4885 |
| US-20100004288-A1 | FUNGICIDAL AMIDES | NAT1, NOX1, Q6ZSR9 | ALDH1A1 662/4885L3MBTL1 1442/4885TDP1 1407/4885 |
| US-20150291578-A1 | FUNGICIDAL AZOCYCLIC AMIDES | ARG1, NAT1, CHRM1 | ALDH1A1 999/4885L3MBTL1 1495/4885TDP1 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.