Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24015882 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP1A2KDM4ETACR3GAA | |
| SCHEMBL19322907 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP1A2KDM4ETACR3GAA | |
| SCHEMBL24015880 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP1A2KDM4ETACR3GAA | |
| SCHEMBL11368716 | 0.84 | ALDH1A1 (0.49) | ALDH1A1CYP1A2KDM4ETACR3SMN1; SMN2 | |
| SCHEMBL27228935 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP1A2KDM4ETACR3GAA | |
| SCHEMBL13157233 | 0.81 | PARP1 (0.52) | ALDH1A1CYP1A2KDM4EGAASMN1; SMN2 | |
| SCHEMBL20919515 | 0.81 | PARP1 (0.52) | ALDH1A1CYP1A2KDM4EGAASMN1; SMN2 | |
| SCHEMBL12975784 | 0.81 | PARP1 (0.52) | ALDH1A1CYP1A2KDM4EGAASMN1; SMN2 | |
| SCHEMBL19318488 | 0.81 | RIPK1 (0.47) | ALDH1A1CYP1A2KDM4ETACR3GAA | |
| SCHEMBL25587524 | 0.81 | RIPK1 (0.47) | ALDH1A1CYP1A2KDM4ETACR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | ALDH1A1 1148/4885CYP1A2 472/4885KDM4E 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.