Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19325533 | 0.81 | AKR1C4 (0.47) | HPGDALDH1A1POLB | |
| SCHEMBL23067401 | 0.78 | ALOX5 (0.45) | NPC1RAB9AHPGDSMN1; SMN2ALOX5 | |
| SCHEMBL3607272 | 0.77 | KLKB1 (0.61) | KLKB1PLAUPLATP2RX7F2 | |
| SCHEMBL28763778 | 0.76 | HPGD (0.53) | NPC1RAB9AKLKB1PLAUPLAT | |
| SCHEMBL19326233 | 0.75 | CDK1 (0.65) | P2RX7P2RX1P2RX4TMPRSS4 | |
| SCHEMBL4408502 | 0.74 | ALOX5 (0.59) | NPC1RAB9AHPGDALOX5ALDH1A1 | |
| SCHEMBL8288031 | 0.73 | NPC1 (0.70) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11575167 | 0.72 | ALDH1A1 (0.60) | RAB9AHPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16456496 | 0.71 | ALOX5 (0.56) | NPC1RAB9AKLKB1HPGDALOX5 | |
| SCHEMBL17748294 | 0.70 | ALOX5 (0.68) | HPGDALOX5ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | NPC1 1693/4885RAB9A 4095/4885KLKB1 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.