Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | PLAT | P00750 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600310 | 0.85 | MAPT (0.53) | P2RX7MAPTKDM4EALDH1A1POLB | |
| SCHEMBL4384455 | 0.84 | TAS1R3 (0.60) | P2RX7MAPTKDM4EALDH1A1TAS1R3 | |
| SCHEMBL406614 | 0.83 | POLB (0.69) | MAPTKDM4EALDH1A1POLBCA1 | |
| SCHEMBL10558954 | 0.82 | ALDH1A1 (0.50) | KLKB1P2RX7MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2452557 | 0.82 | POLB (0.67) | MAPTKDM4EALDH1A1POLBCA1 | |
| SCHEMBL8409274 | 0.81 | ALDH1A1 (0.54) | KLKB1PLAUPLATF2F10 | |
| SCHEMBL17738209 | 0.81 | KAT6A (0.54) | KLKB1P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL16054667 | 0.81 | TAS1R3 (0.52) | P2RX7MAPTKDM4EALDH1A1TAS1R3 | |
| SCHEMBL25364346 | 0.79 | PBRM1 (0.53) | KLKB1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL28763778 | 0.79 | HPGD (0.53) | KLKB1PLAUPLATF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083314-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100029685-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2010-02-04 | — | — | US | disclosed |
| CN-101553486-A | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators | NEUROSEARCH AS (DK) | 2009-10-07 | — | — | CN | disclosed |
| EP-2079734-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NeuroSearch A/S (DK) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049864-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029685-A1 | OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | CHRNA3, CHRNA5, CHRNB3 | KLKB1 2194/4885PLAU 3811/4885PLAT 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.