SCHEMBL19326432

SCHEMBL19326432

Cc1ccc(C2COC(C)OC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 0.39
ALOX15 P16050 1/20 0.39
SLC18A3 Q16572 1/20 0.39
MAP1LC3B Q9GZQ8 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 2/20 0.36
ATM Q13315 2/20 0.36
TP53 P04637 2/20 0.36
RAB9A P51151 3/20 0.35
HTT P42858 2/20 0.35
ACHE P22303 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LIPE Q05469 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930154 0.83 ALOX12 (0.39) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL19185603 0.82 ALOX12 (0.36) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL19853360 0.81 SLC18A3 (0.40) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL10185051 0.79 ALOX12 (0.42) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL14259317 0.78 SLC18A3 (0.39) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL21305418 0.78 CYP3A4 (0.38) TDP1CYP3A4CYP2C9CYP2C19HTR2A
SCHEMBL20850056 0.77 HTR2A (0.35) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL15274523 0.76 ALOX12 (0.40) ALOX12ALOX15SLC18A3MAP1LC3BALDH1A1
SCHEMBL19509352 0.75 SLC18A3 (0.35) ALOX12ALOX15SLC18A3ALDH1A1MAPT
SCHEMBL21360903 0.75 TNKS (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584853-B2 Dichroic dye and liquid crystal composition DIC CORPORATION (JP) 2023-02-21 US disclosed
US-20220073750-A1 DICHROIC DYE AND LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2022-03-10 US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 US disclosed
US-10947403-B2 Dispersion and inkjet ink composition, light conversion layer, and liquid crystal display element using the dispersion DIC CORPORATION (JP) 2021-03-16 US disclosed
US-10913896-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2021-02-09 US disclosed
US-10752838-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2020-08-25 US disclosed
US-20200264461-A1 LIGHT CONVERSION FILM AND IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2020-08-20 US disclosed
US-10465113-B2 Nematic liquid crystal composition, and liquid crystal display element manufactured using same DIC CORPORATION (JP) 2019-11-05 US disclosed
US-20190203122-A1 SPONTANEOUS ORIENTATION AID FOR LIQUID CRYSTAL COMPOSITION, COMPOUND SUITABLE FOR SAID SPONTANEOUS ORIENTATION AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-07-04 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-20190025656-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR PRODUCING SAME DIC CORPORATION (JP) 2019-01-24 US disclosed
US-20180208846-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2018-07-26 US disclosed
US-20180171234-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-06-21 US disclosed
US-20180030346-A1 NEMATIC LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT MANUFACTURED USING SAME DIC CORPORATION (JP) 2018-02-01 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822301-B2 Alkenyl ether compound and a liquid crystal composition using the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-20170253800-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190203122-A1 SPONTANEOUS ORIENTATION AID FOR LIQUID CRYSTAL COMPOSITION, COMPOUND SUITABLE FOR SAID SPONTANEOUS ORIENTATION AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SKP1, SIK1, MINK1 ALOX12 1581/4885ALOX15 1153/4885SLC18A3 2189/4885
US-10465113-B2 Nematic liquid crystal composition, and liquid crystal display element manufactured using same LBR, VSIR, KIF23 ALOX12 3981/4885ALOX15 3859/4885SLC18A3 1946/4885
US-20180030346-A1 NEMATIC LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT MANUFACTURED USING SAME LBR, VSIR, KIF23 ALOX12 3981/4885ALOX15 3859/4885SLC18A3 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.