SCHEMBL193288

SCHEMBL193288

CCCC(OC(CCC)S(=O)(=O)O)S(=O)(=O)O.[NaH]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.37
HDAC2 Q92769 3/20 0.37
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37
HRH1 P35367 1/20 0.37
DRD3 P35462 1/20 0.37
SLC6A3 Q01959 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
NFKB1 P19838 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HDAC7 Q8WUI4 3/20 0.35
HDAC8 Q9BY41 3/20 0.35
HDAC6 Q9UBN7 3/20 0.35
HDAC9 Q9UKV0 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37544 0.98 HDAC1 (0.39) HDAC1HDAC2CHRM1AKR1A1CHRM3
Hydrochloric Acid SCHEMBL20590135 0.95 HDAC1 (0.37) HDAC1HDAC2CHRM1AKR1A1CHRM3
Maleic Acid SCHEMBL28227364 0.84 HCAR2 (0.40) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL420985 0.84 TP53 (0.42) TDP1CYP3A4TSHRCA1CA2
SCHEMBL27731097 0.83 TP53 (0.47) CA1CA2TP53FDPS
SCHEMBL22361234 0.83 TSHR (0.46) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL419967 0.82 TP53 (0.50) CA1TP53FDPSRECQL
SCHEMBL10569914 0.81 CA1 (0.39) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL754167 0.80 TP53 (0.48) CA1CA2TP53FDPS
SCHEMBL754171 0.80 TP53 (0.48) CA1CA2TP53FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633609-A1 LIPID NANOPARTICLES LYOPHILIZATION METHODS AND COMPOSITIONS Global Life Sciences Solutions Canada ULC (CA) 2025-10-22 EP claimed
EP-4512475-A2 COMPOSITIONS COMPRISING AN RNA POLYMERASE INHIBITOR AND CYCLODEXTRIN FOR TREATING VIRAL INFECTIONS Gilead Sciences, Inc. (US) 2025-02-26 EP claimed
EP-3651734-B1 COMPOSITIONS COMPRISING AN RNA POLYMERASE INHIBITOR AND CYCLODEXTRIN FOR TREATING VIRAL INFECTIONS GILEAD SCIENCES INC (US) 2024-11-13 EP claimed
WO-2024126423-A1 LIPID NANOPARTICLES LYOPHILIZATION METHODS AND COMPOSITIONS Precision NanoSystems ULC (CA) 2024-06-20 WO claimed
US-20240148700-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MACULAR DEGENERATION ALDEYRA THERAPEUTICS, INC. 2024-05-09 US claimed
US-11975017-B2 Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections GILEAD SCIENCES, INC. (US) 2024-05-07 US claimed
CN-117982682-A Compositions comprising an RNA polymerase inhibitor and a cyclodextrin for treating viral infections 吉利德科学公司 2024-05-07 CN claimed
US-20240091251-A1 COMPOSITIONS COMPRISING AN RNA POLYMERASE INHIBITOR AND CYCLODEXTRIN FOR TREATING VIRAL INFECTIONS GILEAD SCIENCES, INC. 2024-03-21 US claimed
CN-111093627-B Compositions comprising an RNA polymerase inhibitor and a cyclodextrin for treating viral infections 吉利德科学公司 2024-03-08 CN claimed
US-20240024341-A1 INHALATION FORMULATIONS OF 1`-CYANO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS GILEAD SCIENCES, INC. 2024-01-25 US claimed
EP-1819350-A2 PHARMACEUTICAL FORMULATIONS CYTIDINE ANALOGS AND DERIVATIVES SuperGen, Inc. (US) 2007-08-22 EP claimed
EP-1819227-A1 PHARMACEUTICAL FORMULATION OF DECITABINE SuperGen, Inc. (US) 2007-08-22 EP claimed
WO-2006071491-A1 PHARMACEUTICAL FORMULATION OF DECITABINE SUPERGEN, INC. (US) 2006-07-06 WO claimed
US-20060128653-A1 Pharmaceutical formulation of decitabine SUPERGEN, INC. 2006-06-15 US claimed
WO-2006063111-A2 PHARMACEUTICAL FORMULATIONS CYTIDINE ANALOGS AND DERIVATIVES SUPERGEN, INC. (US) 2006-06-15 WO claimed
US-20060128654-A1 Pharmaceutical formulation of cytidine analogs and derivatives SUPERGEN, INC. 2006-06-15 US claimed
US-20040053888-A1 Cyclodextrin-containing pharmaceutical preparation DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-03-18 US claimed
EP-1348432-A1 CYCLODEXTRIN-CONTAINING PHARMACEUTICAL PREPARATION DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-10-01 EP claimed
US-6596706-B1 For the treatment of circulatory diseases cerebral diseases DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-07-22 US claimed
EP-1029872-A1 PIPERAZINE-CYCLODEXTRIN COMPLEXES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-08-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240091251-A1 COMPOSITIONS COMPRISING AN RNA POLYMERASE INHIBITOR AND CYCLODEXTRIN FOR TREATING VIRAL INFECTIONS CTDSP1, RNGTT, POLRMT HDAC1 126/4885HDAC2 307/4885CHRM1 4756/4885
US-20240148700-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MACULAR DEGENERATION PDE6C, PDE6H, PDE6D HDAC1 2580/4885HDAC2 2755/4885CHRM1 2181/4885
US-11975017-B2 Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections CTDSP1, RNGTT, POLRMT HDAC1 126/4885HDAC2 307/4885CHRM1 4756/4885
US-20240024341-A1 INHALATION FORMULATIONS OF 1`-CYANO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS SLC29A1, SLC28A1, RNMT HDAC1 2355/4885HDAC2 3733/4885CHRM1 76/4885
US-20040053888-A1 Cyclodextrin-containing pharmaceutical preparation SLCO2B1, RPS27L, SEC23IP HDAC1 4304/4885HDAC2 3680/4885CHRM1 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.