Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329572 | 0.88 | MEN1 (0.51) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329667 | 0.85 | CASP6 (0.47) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329412 | 0.81 | CASP6 (0.48) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329318 | 0.79 | CASP6 (0.68) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329690 | 0.79 | ALDH1A1 (0.48) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329634 | 0.79 | HDAC3 (0.53) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329542 | 0.77 | CA1 (0.56) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19329465 | 0.77 | CASP6 (0.49) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329451 | 0.77 | CASP6 (0.82) | CASP6ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329557 | 0.77 | CASP6 (0.53) | CASP6ALDH1A1KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | claimed |
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |