SCHEMBL19330109

SCHEMBL19330109

Cc1cccc(C(=O)O)c1N1C(=O)CSC1c1ccc(F)cc1

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 19/20 0.73
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28645399 0.90 HTR7 (0.71) HTR7MEN1KMT2A
SCHEMBL19330105 0.90 HTR7 (0.71) HTR7MEN1KMT2A
SCHEMBL28625742 0.90 HTR7 (0.58) HTR7
SCHEMBL28634811 0.89 HTR7 (0.60) HTR7
SCHEMBL28636511 0.87 HTR7 (0.61) HTR7MEN1KMT2A
SCHEMBL28641312 0.87 HTR7 (0.64) HTR7MEN1KMT2A
SCHEMBL28629779 0.87 HTR7 (0.61) HTR7MEN1KMT2A
SCHEMBL28636466 0.86 HTR7 (0.66) HTR7
SCHEMBL28631039 0.86 PTGS2 (0.61) HTR7
SCHEMBL28641117 0.85 HTR7 (0.65) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3426246-A1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF National Health Research Institutes (TW) 2019-01-16 EP disclosed
WO-2017155910-A1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2017-09-14 WO disclosed