Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.61 |
| ▸ | GFER | P55789 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625742 | 0.88 | HTR7 (0.58) | HTR7 | |
| SCHEMBL28634791 | 0.87 | HTR7 (0.61) | HTR7GFERKMT2AMEN1PTGS2 | |
| SCHEMBL28634811 | 0.87 | HTR7 (0.60) | HTR7 | |
| SCHEMBL19330109 | 0.87 | HTR7 (0.73) | HTR7KMT2AMEN1 | |
| SCHEMBL28631039 | 0.84 | PTGS2 (0.61) | HTR7PTGS2PTGS1 | |
| SCHEMBL28641312 | 0.80 | HTR7 (0.64) | HTR7GFERKMT2AMEN1 | |
| SCHEMBL28645399 | 0.77 | HTR7 (0.71) | HTR7KMT2AMEN1 | |
| SCHEMBL19330105 | 0.77 | HTR7 (0.71) | HTR7KMT2AMEN1 | |
| SCHEMBL28627674 | 0.77 | HTR7 (0.62) | HTR7GFERKMT2AMEN1 | |
| SCHEMBL19306376 | 0.76 | HTR7 (1.00) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |