Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30642997 | 0.75 | PIM1 (0.49) | MEN1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL8574510 | 0.74 | EGFR (0.70) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL8574541 | 0.73 | EGFR (1.00) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL31140515 | 0.72 | WEE1 (0.49) | MEN1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL6068151 | 0.69 | MEN1 (0.62) | MEN1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL27977953 | 0.69 | DYRK1A (0.50) | ALOX5HTR2A | |
| SCHEMBL27856192 | 0.69 | DYRK1A (0.55) | ALOX5AURKATPX2GSK3BIDO1 | |
| SCHEMBL9812827 | 0.68 | ALOX5 (0.58) | MEN1MAPTKMT2AALOX15CYP3A4 | |
| Methane SCHEMBL28101908 | 0.67 | MEN1 (0.60) | MEN1MAPTKMT2AALOX15CYP3A4 | |
| SCHEMBL17982251 | 0.67 | GPR84 (0.55) | MEN1MAPTKMT2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066606-A1 | PYRANOINDOLE COMPOUNDS AND USES THEREOF | NOVOGEN RESEARCH PTY LTD (AU) | 2011-06-09 | — | — | WO | disclosed |