Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.49 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31559172 | 1.00 | PSMB1 (0.49) | PSMB1PSMB5TYMSPDE4BHTR2A | |
| SCHEMBL1500297 | 0.87 | HTR2A (0.39) | PSMB1PSMB5PDE4BHTR2AHTR2C | |
| SCHEMBL25910676 | 0.80 | HTR2C (0.39) | TYMSHTR2AHTR2CMIF | |
| SCHEMBL16166662 | 0.80 | BRPF1 (0.37) | PSMB1PSMB5TYMSHTR2AALDH1A1 | |
| SCHEMBL28592437 | 0.80 | PIM1 (0.39) | TYMSHTR2AHTR2CDPP4ALDH1A1 | |
| SCHEMBL23775716 | 0.80 | RORA (0.36) | PSMB1PSMB5HTR2AALDH1A1HTT | |
| SCHEMBL30033880 | 0.80 | PIM1 (0.39) | TYMSHTR2AHTR2CDPP4ALDH1A1 | |
| SCHEMBL30349862 | 0.80 | BRPF1 (0.37) | PSMB1PSMB5TYMSHTR2AALDH1A1 | |
| SCHEMBL9919029 | 0.77 | PSMB1 (0.46) | PSMB1PSMB5TYMSLMNAMIF | |
| SCHEMBL2117453 | 0.76 | HDAC6 (0.41) | PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426260-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | Fimbrion Therapeutics, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |