Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734880 | 0.83 | TP53 (0.52) | PKMMAPTKDM4ERECQLTP53 | |
| SCHEMBL19333097 | 0.81 | KDM4E (0.43) | MAPTKDM4ETP53GAAPOLB | |
| SCHEMBL21767266 | 0.74 | PKM (0.52) | PKMMAPTTP53GAAKMT2A | |
| SCHEMBL25492286 | 0.74 | PKM (0.52) | SNCAPKMTP53GAAHTT | |
| SCHEMBL19333109 | 0.70 | MEN1 (0.36) | MAPTKDM4EGAAPOLBKMT2A | |
| SCHEMBL8736025 | 0.68 | TP53 (0.52) | PKMMAPTTP53GAAKMT2A | |
| SCHEMBL8736001 | 0.65 | TP53 (0.56) | PKMMAPTKDM4ERECQLTP53 | |
| SCHEMBL8736028 | 0.64 | TP53 (0.52) | PKMKDM4ETP53GAAKMT2A | |
| SCHEMBL25492198 | 0.63 | GAA (0.47) | PKMTP53GAAHTT | |
| SCHEMBL25492175 | 0.63 | GAA (0.47) | PKMMAPTTP53GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757381-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-09-12 | — | — | US | disclosed |